[Genetic association between the reduced amplitude of the P300 and the allele A1 of the gene which codifies the D2 dopamine receptor (DRD2) as possible biological markers for alcoholism].

Abstract excerpt

INTRODUCTION: Over the last twenty years much work has been done to study the P300 in alcoholism. A systematically reduced amplitude, both in patients and in populations at risk (children of alcoholics) was found. Besides, studies on twins indicate that the waves of the evoked potentials are under genetic control. Furthermore, advances in molecular genetic techniques have clarified the part played by the allele...

Topics

• Alcoholism
• Alleles
• Event-Related Potentials, P300
• Gene Expression
• Humans
• Receptors, Dopamine D2