Article
Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high risk for alcoholism.
Biological psychiatry - 1 Jan 1998
Hill S Y, Locke J, Zezza N, Kaplan B, Neiswanger K, Steinhauer S R, Wipprecht G, Xu J
Abstract excerpt
BACKGROUND: There is evidence that both reduction in P300 amplitude and the presence of the A1 allele are risk markers for alcoholism. We hypothesized that demonstration of a relationship between the marker and the trait in young children who had not begun to drink regularly would provide evidenc...
Topics
- Acoustic Stimulation
- Alcoholism
- Alleles
- Child
- Event-Related Potentials, P300
- Female
- Genotype
- Humans
- Male
- Photic Stimulation
- Pregnancy
- Prenatal Exposure Delayed Effects
- Psychiatric Status Rating Scales
- Receptors, Dopamine D2
- Risk Factors