Article
Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high risk for alcoholism.
Biological psychiatry - 1 Jan 1998
Hill S Y, Locke J, Zezza N, Kaplan B, Neiswanger K, Steinhauer S R, Wipprecht G, Xu J
Abstract excerpt
BACKGROUND: There is evidence that both reduction in P300 amplitude and the presence of the A1 allele are risk markers for alcoholism. We hypothesized that demonstration of a relationship between the marker and the trait in young children who had not begun to drink regularly would provide evidence for dopaminergic mediation of the reduction in P300 often seen among high-risk children. A previous association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.