Article
Thiamine deficiency as predisposition to, and consequence of, increased alcohol consumption.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jul 1996
Zimatkin S M, Zimatkina T I
Abstract excerpt
It was found that the activity of the marker thiamine-dependent enzyme, transketolase (TK), was decreased (down to 61-79% of control) in blood, liver and brain of inbred rats following a 6-month consumption of 15% ethanol as their only source of drinking fluid. After ethanol withdrawal, the enzyme activity was gradually restored, but did not reach the control values until 1 month following cessation of alcohol...
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