Article
Large transcripts and sequence from a polymorphic 170 kb MHC region implicated in susceptibility to autoimmune disease.
Immunogenetics - 1 Jan 1994
Marshall B, Leelayuwat C, Abraham L J, Pinelli M, Dawkins R L
Abstract excerpt
We have used the novel strategy of overlapping yeast artificial chromosome (YAC) clones to localize a series of new transcripts within a 170 kb region of the human major histocompatibility complex (MHC), containing genes likely to be of importance for disease susceptibility. Using cloned genomic probes we have further localized these transcripts to a region 15 kilobases (kb) centromeric of HLA-B. In the liver...
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