Article
Hypersensitivity to oxygen is a uniform and secondary defect in Fanconi anemia cells.
Mutation research - 1 Oct 1993
Saito H, Hammond A T, Moses R E
Abstract excerpt
Cells from patients with Fanconi anemia (FA) frequently show an increased sensitivity to DNA crosslinking agents such as mitomycin C (MMC). FA cells also show abnormal sensitivity to oxygen tension. In order to examine the correlation between the two cellular defects in FA, several FA fibroblast lines were tested for their sensitivity to MMC and oxygen by colony-formation frequency. The sensitivity to MMC in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.