Article
Rubella virus-specific cytotoxic T-lymphocyte responses: identification of the capsid as a target of major histocompatibility complex class I-restricted lysis and definition of two epitopes.
Journal of virology - 1 Oct 1993
Lovett A E, Hahn C S, Rice C M, Frey T K, Wolinsky J S
Abstract excerpt
The role of major histocompatibility complex (MHC) class I-restricted CD8+ cytotoxic T lymphocytes in immunity to rubella virus (RV) infection is unknown. Lymphocytes of RV-immune individuals were prestimulated on an RV-infected MHC class I-matched (or partially matched) fibroblast monolayer whic...
Topics
- Adult
- Alleles
- Amino Acid Sequence
- Antibody Formation
- CD8 Antigens
- Capsid
- Cells, Cultured
- Cytotoxicity, Immunologic
- Epitopes
- Female
- Genes, MHC Class I
- Genetic Vectors
- Histocompatibility Antigens Class I
- Humans
- Immunity, Cellular
