Article
Identification of potential CTL epitopes of bovine RSV using allele-specific peptide motifs from bovine MHC class I molecules.
Veterinary immunology and immunopathology - 1 Nov 1996
Gaddum R M, Ellis S A, Willis A C, Cook R S, Staines K A, Thomas L H, Taylor G
Abstract excerpt
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in young infants and housed calves. Depletion of CD8+ lymphocytes from calves inhibited their ability to clear the virus from the nasopharynx and lungs. To study these cells further, a cytotoxic T lymphocyte (CTL) assay was established. CTL could be demonstrated in the peripheral blood of gnotobiotic calves 7-10 days post...
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