Article
[Mechanisms of the effect of interferon (IFN) therapy in patients with type B and C chronic hepatitis].
[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 May 1993
Karino Y
Abstract excerpt
The relationship between 2', 5'-oligoadenylate synthetase (2-5AS) and HLA class I antigen in the hepatocyte of patients with type B or type C chronic hepatitis with and without interferon (IFN) therapy was investigated. The expression of HLA class I antigen of hepatocytes of biopsied specimen and PBL HLA class I antigen expression showed relevancy. Then, the HLA antigen expression of peripheral blood lymphocyte...
Topics
- 2',5'-Oligoadenylate Synthetase
- Adult
- Aged
- Chronic Disease
- Genotype
- Hepacivirus
- Hepatitis B
- Hepatitis C
- Histocompatibility Antigens Class I
- Humans
- Interferons
