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Article

Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry.

Journal of virology - 1 May 1993

Mori K, Ringler D J, Desrosiers R C

Abstract excerpt

Virus derived from the infectious, pathogenic, molecular clone of simian immunodeficiency virus (SIV) called SIVmac239 replicates poorly in primary rhesus monkey alveolar macrophage cultures. Variants with three to nine amino acid changes in the envelope replicate 100 to 1,000 times more efficien...

Topics

Animals
Base Sequence
CD4 Antigens
Cell Line
DNA, Viral
Genes, env
Genetic Variation
Macaca mulatta
Macrophages
Molecular Sequence Data
Polymerase Chain Reaction
RNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Virus

Simian Immunodeficiency Virus

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 7682627
DOI: 10.1128/JVI.67.5.2807-2814.1993
PMCID: PMC237605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7682627-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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