Article
Analysis of the human T-cell response to picornaviruses: identification of T-cell epitopes close to B-cell epitopes in poliovirus.
Journal of virology - 1 Mar 1993
Graham S, Wang E C, Jenkins O, Borysiewicz L K
Abstract excerpt
Little is known about the nature and specificity of T-cell-mediated responses to picornaviruses in humans. In this study, the nature of the T-cell response to seven picornaviruses, including polioviruses, coxsackieviruses B3 and B4, human rhinovirus 14, and encephalomyocarditis virus, was determi...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Viral
- B-Lymphocytes
- CD4 Antigens
- CD8 Antigens
- Capsid
- Capsid Proteins
- Cell Division
- Cells, Cultured
- Cross Reactions
- Epitopes
- Humans
- Lymphocyte Activation
- Molecular Sequence Data
- Peptide Fragments
- Phenotype
- Picornaviridae