Article
Proteus mirabilis urease: transcriptional regulation by UreR.
Journal of bacteriology - 1 Jan 1993
Nicholson E B, Concaugh E A, Foxall P A, Island M D, Mobley H L
Abstract excerpt
Proteus mirabilis urease catalyzes the hydrolysis of urea, initiating the formation of urinary stones. The enzyme is critical for kidney colonization and the development of acute pyelonephritis. Urease is induced by urea and is not controlled by the nitrogen regulatory system (ntr) or catabolite repression. Purified whole-cell RNA from induced and uninduced cultures of P. mirabilis and Escherichia coli harboring...
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