[The role of mitochondrial DNA in the origin of regular trisomy 21].

Article

[The role of mitochondrial DNA in the origin of regular trisomy 21].

TSitologiia i genetika - 1 Jan 2000

Arbuzova S B

Abstract excerpt

Hypothesis about cytoplasmic heredity and the influence of mitochondrial DNA mutations on the pathogenesis of 21 trisomy has been suggested. It explains the association of increased risk of trisomy with the maternal age, malignant diseases, autoimmune processes, other pathologies and with the ori...

Topics

Chromosomes, Human, Pair 21
DNA, Mitochondrial
Down Syndrome
Female
Humans
Male
Mutation

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