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Article

[The role of mitochondrial DNA in the origin of regular trisomy 21].

TSitologiia i genetika - 1 Jan 2000

Arbuzova S B

Abstract excerpt

Hypothesis about cytoplasmic heredity and the influence of mitochondrial DNA mutations on the pathogenesis of 21 trisomy has been suggested. It explains the association of increased risk of trisomy with the maternal age, malignant diseases, autoimmune processes, other pathologies and with the origin of paternal 21 chromosome.

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Share to Chromosomes, Human, Pair 21
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Source

Identifiers

PMID: 7676512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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