Article
Identification of subsets of neuroblastomas by combined histopathologic and N-myc analysis.
Journal of the National Cancer Institute - 4 Oct 1995
Shimada H, Stram D O, Chatten J, Joshi V V, Hachitanda Y, Brodeur G M, Lukens J N, Matthay K K, Seeger R C
Abstract excerpt
BACKGROUND: Neuroblastomas show different histopathologic phenotypes, and the tumor cells can carry normal or multiple copies of the N-myc proto-oncogene (MYCN). Studies of the N-myc gene and histopathology of untreated primary neuroblastomas have demonstrated that both these factors are important in risk assessment. PURPOSE: Our purpose was to determine if there are any associations between N-myc gene copy...
Topics
- Chi-Square Distribution
- Child
- Child, Preschool
- Disease Progression
- Gene Amplification
- Genes, myc
- Humans
- Neoplasm Staging
- Neuroblastoma
- Phenotype
- Prognosis