Article
Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients.
American journal of human genetics - 1 Aug 1995
Aoyama T, Souri M, Ueno I, Kamijo T, Yamaguchi S, Rhead W J, Tanaka K, Hashimoto T
Abstract excerpt
Two overlapping cDNA clones (1,991 bp and 736 bp, respectively) encoding the precursor of human mitochondrial very-long-chain acyl-coenzyme A dehydrogenase (VLCAD) were cloned and sequenced. The cDNA inserts of these clones together encompass a region of 2,177 bases, encoding the entire protein o...
Topics
- Acyl-CoA Dehydrogenase, Long-Chain
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Fatty Acid Desaturases
- Fibroblasts
- Humans
- Lipid Metabolism, Inborn Errors
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction