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ACBD5 deficiency causes a defect in peroxisomal very long-chain fatty acid metabolism

31 Oct 2016

Abstract excerpt

Background Acyl-CoA binding domain containing protein 5 (ACBD5) is a peroxisomal membrane protein with a cytosolic acyl-CoA binding domain. Because of its acyl-CoA binding domain, ACBD5 has been assumed to function as an intracellular carrier of acyl-CoA esters. In addition, a role for ACBD5 in pexophagy has been suggested. However, the precise role of ACBD5 in peroxisomal metabolism and/or functioning has not...

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PMID: 27799409
DOI: 10.1136/jmedgenet-2016-104132

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