Article
Cloning and characterization of human very-long-chain acyl-CoA dehydrogenase cDNA, chromosomal assignment of the gene and identification in four patients of nine different mutations within the VLCAD gene.
Human molecular genetics - 1 Apr 1996
Andresen B S, Bross P, Vianey-Saban C, Divry P, Zabot M T, Roe C R, Nada M A, Byskov A, Kruse T A, Neve S, Kristiansen K, Knudsen I, Corydon M J, Gregersen N
Abstract excerpt
Very-long-chain acyl-CoA dehydrogenase (VLCAD) is one of four straight-chain acyl-CoA dehydrogenase (ACD) enzymes, which are all nuclear encoded mitochondrial flavoproteins catalyzing the initial step in fatty acid beta-oxidation. We have used the very fast, Rapid Amplification of cDNA Ends (RACE) based strategy to obtain the sequence of cDNAs encoding human VLCAD from placenta and fibroblasts. Alignment of the...
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