Article
Characterization of the Escherichia coli gcvR gene encoding a negative regulator of gcv expression.
Journal of bacteriology - 1 Sept 1995
Ghrist A C, Stauffer G V
Abstract excerpt
The Escherichia coli glycine cleavage enzyme system catalyzes the cleavage of glycine, generating CO2, NH3, and a one-carbon unit. Expression of the operon encoding this enzyme system (gcv) is induced in the presence of glycine and repressed in the presence of purines. In this study, a mutant with high-level constitutive expression of a gcvT-lacZ gene fusion was isolated. The mutation in this strain was...
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