Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GcvR interacts with GcvA to inhibit activation of the Escherichia coli glycine cleavage operon.

Microbiology (Reading, England) - 1 Aug 2001

Ghrist Angela C, Heil Gary, Stauffer George V

Abstract excerpt

The Escherichia coli glycine cleavage enzyme system, encoded by the gcvTHP operon, catalyses the oxidative cleavage of glycine to CO(2), NH(3) and a one-carbon methylene group. Transcription of the gcv operon is positively regulated by GcvA and negatively regulated by GcvA and GcvR. Using a LexA-based system for analysing protein heterodimerization, it is shown that GcvR interacts directly with GcvA in vivo to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Oxidoreductases
Share to Carrier Proteins
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Multienzyme Complexes

Share to Operon

Share to Repressor Proteins

Share to Transferases

Source

Identifiers

PMID: 11495998
DOI: 10.1099/00221287-147-8-2215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GcvR interacts with GcvA to inhibit activation of the Escherichia coli glycine cleavage operon.PMID 11495998Read ↗

Characterization of the Escherichia coli gcvR gene encoding a negative regulator of gcv expression.Semantic proximity Read ↗

Roles of the GcvA and PurR proteins in negative regulation of the Escherichia coli glycine cleavage enzyme system.Semantic proximity Read ↗

DNA binding sites of the LysR-type regulator GcvA in the gcv and gcvA control regions of Escherichia coli.Semantic proximity Read ↗

The gcvB gene encodes a small untranslated RNA involved in expression of the dipeptide and oligopeptide transport systems in Escherichia coli.Semantic proximity Read ↗

The Escherichia coli gcvT gene encoding the T-protein of the glycine cleavage enzyme system.Semantic proximity Read ↗

Characterization of the Escherichia coli gcv operon.Semantic proximity Read ↗

The Escherichia coli glycine transport system and its role in the regulation of the glycine cleavage enzyme system.Semantic proximity Read ↗

A glycine-dependent riboswitch that uses cooperative binding to control gene expression.Semantic proximity Read ↗

Cloning, and molecular characterization of the GCV1 gene encoding the glycine cleavage T-protein from Saccharomyces cerevisiae.Semantic proximity Read ↗

GcvA binding site 1 in the gcvTHP promoter of Escherichia coli is required for GcvA-mediated repression but not for GcvA-mediated activation.Semantic proximity Read ↗

GcvA-mediated activation of gcvT-lacZ expression involves the carboxy-terminal domain of the alpha subunit of RNA polymerase.Semantic proximity Read ↗

Escherichia coli cis- and trans-acting mutations that increase glyA gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.