Article
Hypertrophic cardiomyopathy--pathology and pathogenesis.
Histopathology - 1 Jun 1995
Davies M J, McKenna W J
Abstract excerpt
Genes on five loci on separate chromosomes are responsible for a familial disease in which all or part of the ventricular muscle undergoes thickening with a histological picture of irregular hypertrophy and disorganized arrangement of myocytes (disarray). The three genes identified so far encode for beta heavy chain myosin (chromosome 14), troponin T (chromosome 1) and alpha tropomyosin (chromosome 15). It is...
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