Article
The inheritance of hypertrophic cardiomyopathy.
Pediatric cardiology - 1 Jan 2000
Burch M, Blair E
Abstract excerpt
The inheritance of hypertrophic cardiomyopathy is autosomal dominant, "sporadic" cases are now recognised to be uncommon. In the past 5 years molecular genetic advances have isolated >100 different mutations in genes encoding sarcomeric proteins. The cardiac morphology and prognosis are linked to...
Topics
- Age Distribution
- Cardiomyopathy, Hypertrophic
- DNA Mutational Analysis
- Echocardiography
- Genes, Dominant
- Genetic Testing
- Genetic Variation
- Humans
- Mutation
- Myosins
- Penetrance
- Polymorphism, Genetic
- Prognosis