Article
Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy.
Human molecular genetics - 1 Jan 1995
Watkins H, Seidman J G, Seidman C E
Abstract excerpt
Familial hypertrophic cardiomyopathy is an autosomal dominant disorder manifesting as cardiac hypertrophy in the absence of increased cardiac work load, which has been studied as a model of myocardial hypertrophy in humans. Hypertrophic cardiomyopathy is genetically heterogeneous with three known...
Topics
- Alleles
- Cardiomegaly
- Cardiomyopathy, Hypertrophic
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 15
- Genes, Dominant
- Humans
- Mutation
- Troponin
- Troponin T