Article
Identification of a PIG-A related processed gene on chromosome 12.
Human genetics - 1 Jun 1995
Nagarajan S, Brown C J, Medof M E
Abstract excerpt
PIG-A, the gene encoding the glycoinositol phospholipid anchor synthetic element that is defective in paroxysmal nocturnal hemoglobinuria (PNH), resides on the X chromosome. In the course of analyses of PIG-A genetic alterations in PNH patients, polymerase chain reaction (PCR) amplification of re...
Topics
- Base Sequence
- Blotting, Southern
- Chromosome Mapping
- Chromosomes, Human, Pair 12
- Genetic Variation
- Glycosylphosphatidylinositols
- Hemoglobinuria, Paroxysmal
- Humans
- Membrane Proteins
- Molecular Sequence Data
- Multigene Family
- Polymerase Chain Reaction
- Sequence Homology, Amino Acid