Article
Complete nucleotide sequence of a cytopathic hepatitis A virus strain isolated in Italy.
Virus research - 1 May 1995
Beneduce F, Pisani G, Divizia M, Panà A, Morace G
Abstract excerpt
The molecular basis of the cytopathic effect induced in cell culture by some hepatitis A virus (HAV) strains and variants has not been determined. In order to assess the molecular mechanism(s) underlying this particular phenotype the genome of an Italian cytopathic isolate (strain FG) was sequenced from cDNAs obtained by RT-PCR. Sequence analysis revealed the presence of mutations common to either adapted or...
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