Article
Genetic variability of hepatitis A virus strain HAF-203 isolated in Brazil and expression of the VP1 gene in Escherichia coli.
Memorias do Instituto Oswaldo Cruz - 1 Nov 2006
Baptista Marcia L, Silva Messias, Lima Maria Amélia de, Yoshida Clara Ft, Gaspar Ana Maria C, Galler Ricardo
Abstract excerpt
The hepatitis A virus (HAV) HAF-203 strain was isolated from an acute case of HAV infection. The primary isolation of HAF-203 in Brazil and its adaptation to the FRhK-4 cell lineage allowed the production of large amounts of viral particles enabling molecular characterization of the first HAV isolate in Brazil. The aim of our study was to determine the nucleotide sequence of the HAF-203 strain genome, compare it...
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