Article
Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C.
Nature - 31 Aug 1995
Zhou X, Benson K F, Ashar H R, Chada K
Abstract excerpt
Growth is one of the fundamental aspects in the development of an organism. Classical genetic studies have isolated four viable, spontaneous mouse mutants disrupted in growth, leading to dwarfism. Pygmy is unique among these mutants because its phenotype cannot be explained by aberrations in the growth hormone-insulin-like growth factor endocrine pathway. Here we show that the pygmy phenotype arises from the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.