Article
Effects of MHC-encoded TAP1 and TAP2 gene polymorphism and matching on kidney graft rejection.
Transplantation - 15 Aug 1995
Chevrier D, Giral M, Braud V, Bourbigot B, Muller J Y, Bignon J D, Soulillou J P
Abstract excerpt
The products of TAP1 and TAP2 genes, recently mapped within the MHC class II region, are involved in antigen presentation by MHC class I molecules, especially in the transport of endogenous peptides. As for most MHC genes, a polymorphism has been described and the possibility that it could influe...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Alleles
- Base Sequence
- Genes, MHC Class II
- Graft Rejection
- Histocompatibility Antigens Class I
- Humans
- Kidney Transplantation
- Molecular Sequence Data
- Polymorphism, Genetic
- Tissue Donors