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Article

Phenotypic variation in Haemophilus influenzae: the interrelationship of colony opacity, capsule and lipopolysaccharide.

Microbial pathogenesis - 1 Feb 1995

Roche R J, Moxon E R

Abstract excerpt

H. influenzae type b strains show phase variation between opaque (O) and translucent (T) colony phenotypes. These phenotypic differences have been related to differences in virulence for infant rats. This study shows that the switch between O and T colony phenotypes is associated with variation in the amount of cell-associated capsule in the serotype b strains Rd:b+:01, RM7004 and Eagan. O colonies comprised...

Topics

Blood Bactericidal Activity
Blotting, Western
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Genetic Variation
Haemophilus influenzae
Lipopolysaccharides
Molecular Weight
Phenotype
Polysaccharides

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Identifiers

PMID: 7643742
DOI: 10.1016/s0882-4010(95)90117-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7643742-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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