Article
Identification and characterization of a cell envelope protein of Haemophilus influenzae contributing to phase variation in colony opacity and nasopharyngeal colonization.
Molecular microbiology - 1 Aug 1995
Weiser J N, Chong S T, Greenberg D, Fong W
Abstract excerpt
Haemophilus influenzae undergoes spontaneous phase variation in colony morphology. Organisms from transparent colonies efficiently colonize the nasopharynx in an infant rat model of H. influenzae carriage, whereas organisms from more opaque colonies are deficient at colonization. A genetic approa...
Topics
- Animals
- Bacterial Proteins
- Base Sequence
- DNA Primers
- DNA, Bacterial
- Disease Models, Animal
- Genes, Bacterial
- Genetic Variation
- Haemophilus Infections
- Haemophilus influenzae
- Membrane Proteins
- Molecular Sequence Data
- Nasopharyngeal Diseases
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Restriction Mapping