Catabolite-mediated mutations in alternate toluene degradative pathways in Pseudomonas putida.

doi:10.1128/jb.177.16.4713-4720.1995

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Article

Catabolite-mediated mutations in alternate toluene degradative pathways in Pseudomonas putida.

Journal of bacteriology - 1 Aug 1995

Leddy M B, Phipps D W, Ridgway H F

Abstract excerpt

Pseudomonas putida 54g grew on mineral salts with toluene and exhibited catechol-2,3-dioxygenase (C23O) activity, indicating a meta pathway. After 10 to 15 days on toluene, nondegrading (Tol-) variants approached nearly 10% of total CFU. Auxotrophs were not detected among variants, suggesting selective loss of catabolic function(s). Variant formation was substrate dependent, since Tol- cells were observed on...

Topics

Base Sequence
Benzene Derivatives
Benzoates
Benzyl Alcohol
Benzyl Alcohols
Biodegradation, Environmental
Catechol 2,3-Dioxygenase
Cell Division
Dioxygenases
Genetic Variation
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Oxygenases

Pseudomonas putida

Selection, Genetic

Sequence Deletion

Toluene

Source

Open in PubMed Open full text

Identifiers

PMID: 7642499
DOI: 10.1128/jb.177.16.4713-4720.1995
PMCID: PMC177237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7642499-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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