Article
Less is more: reduced catechol production permits Pseudomonas putida F1 to grow on styrene.
Microbiology (Reading, England) - 1 Nov 2012
George Kevin W, Hay Anthony
Abstract excerpt
Pseudomonas putida F1 is unable to grow on styrene due to the accumulation of 3-vinylcatechol, a toxic metabolite that is produced through the toluene degradation (tod) pathway and causes catechol-2,3-dioxygenase (C23O) inactivation. In this study, we characterized a spontaneous F1 mutant, designated SF1, which acquired the ability to grow on styrene and did not accumulate 3-vinylcatechol. Whereas adaptation to...
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