Infectious cDNA clones of echovirus 12 and a variant resistant against the uncoating inhibitor rhodanine differ in seven amino acids.

doi:10.1128/JVI.69.9.5853-5858.1995

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Article

Infectious cDNA clones of echovirus 12 and a variant resistant against the uncoating inhibitor rhodanine differ in seven amino acids.

Journal of virology - 1 Sept 1995

Kraus W, Zimmermann H, Zimmermann A, Eggers H J, Nelsen-Salz B

Abstract excerpt

Determination of the complete sequences of echovirus 12 and a rhodanine-resistant variant revealed seven amino acid deviations and two additional exchanges not confirmed in all clones. In rhodanine sensitivity assays with infectious cDNAs, it was shown that the biological markers of the original...

Topics

Amino Acid Sequence
Antiviral Agents
Base Sequence
Capsid
Cell Line
Cloning, Molecular
DNA, Complementary
Drug Resistance, Microbial
Enterovirus B, Human
Genetic Variation
Genome, Viral
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Promoter Regions, Genetic
Recombinant Proteins
Rhodamines
Transcription, Genetic

Source

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Identifiers

PMID: 7637032
DOI: 10.1128/JVI.69.9.5853-5858.1995
PMCID: PMC189459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7637032-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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