Article
Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity.
PloS one - 29 Apr 2011
Pelle Roger, Graham Simon P, Njahira Moses N, Osaso Julius, Saya Rosemary M, Odongo David O, Toye Philip G, Spooner Paul R, Musoke Anthony J, Mwangi Duncan M, Taracha Evans L N, Morrison W Ivan, Weir William, Silva Joana C, Bishop Richard P
Abstract excerpt
BACKGROUND: Theileria parva causes an acute fatal disease in cattle, but infections are asymptomatic in the African buffalo (Syncerus caffer). Cattle can be immunized against the parasite by infection and treatment, but immunity is partially strain specific. Available data indicate that CD8(+) T lymphocyte responses mediate protection and, recently, several parasite antigens recognised by CD8(+) T cells have been...
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