Article
Molecular evolution of a central region containing B cell epitopes in the gene encoding the p67 sporozoite antigen within a field population of Theileria parva.
Parasitology research - 1 May 2015
Obara Isaiah, Ulrike Seitzer, Musoke Tony, Spooner Paul R, Jabbar Ahmed, Odongo David, Kemp Stephen, Silva Joana C, Bishop Richard P
Abstract excerpt
Protective immunity induced by the infective sporozoite stage of Theileria parva indicates a potential role for antibodies directed against conserved serologically reactive regions of the major sporozoite surface antigen p67 in vaccination to control the parasite. We have examined the allelic variation and determined the extent of B cell epitope polymorphism of the gene encoding p67 among field isolates...
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