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Article

Association of angiotensin-converting enzyme and angiotensin II type I receptor gene polymorphisms with extreme obesity in Polish individuals.

DNA and cell biology - 1 Aug 2013

Pacholczyk Marta, Ferenc Tomasz, Kowalski Jan, Adamczyk Przemysław, Chojnowski Jacek, Ponikowska Irena

Abstract excerpt

There is strong evidence for the presence of a functional renin-angiotensin system in human adipose tissue. The aim of our study was to investigate the association of polymorphic variants of angiotensin-converting enzyme gene (ACE I/D) and angiotensin II type I receptor gene (AGTR1 A1166C) with extreme obesity and obesity-associated type 2 diabetes mellitus (T2DM) and to examine their combined effect on extremely...

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Case-Control Studies
Diabetes Mellitus, Type 2
Epistasis, Genetic
Genetic Association Studies
Obesity, Morbid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptidyl-Dipeptidase A

Receptor, Angiotensin, Type 1

Source

Identifiers

PMID: 23745680
DOI: 10.1089/dna.2013.2014

Genes

ACE
AGTR1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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