Article
Relationships among 64k autoantibodies, pancreatic beta-cell function, HLA-DR antigens and HLA-DQ genes in patients with insulin-dependent diabetes mellitus in Korea.
The Korean journal of internal medicine - 1 Jan 1995
Lee H C, Cha B S, Nam M S, Song Y D, Lim S K, Kim D H, Huh K B, Koh Y
Abstract excerpt
OBJECTIVES: Among autoantibodies detected in patients with insulin-dependent diabetes mellitus (IDDM), antibodies to 64,000(Mr) islet protein(64k), now recognized as glutamic acid decarboxylase(GAD), appear to be an even more predictive marker of IDDM than islet cytoplasmic antibody (ICA) or insulin autoantibody (IAA). We examined the relationships among 64k autoantibodies, pancreatic beta-cell function, HLA-DR...
Topics
- Adolescent
- Adult
- Alleles
- Animals
- Antibody Specificity
- Asian People
- Autoantibodies
- Autoantigens
- Autoimmune Diseases
- C-Peptide
- Child
