Article
Effects of antioxidants on fiber mutagenesis.
Carcinogenesis - 1 Jul 1995
Hei T K, He Z Y, Suzuki K
Abstract excerpt
Recent studies from this laboratory have shown that asbestos fibers are mutagenic in cultured mammalian cells when assayed using a system that can detect multilocus deletions. Southern analysis of the induced mutants shows that the majority contain large deletions ranging in size from a few thousand to several million basepairs. In the present study, the effects of free radical scavenging enzymes on the cytotoxic...
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