Article
Effects of antioxidants on fiber mutagenesis.
Carcinogenesis - 1 Jul 1995
Hei T K, He Z Y, Suzuki K
Abstract excerpt
Recent studies from this laboratory have shown that asbestos fibers are mutagenic in cultured mammalian cells when assayed using a system that can detect multilocus deletions. Southern analysis of the induced mutants shows that the majority contain large deletions ranging in size from a few thous...
Topics
- Animals
- Antioxidants
- Asbestos, Serpentine
- CHO Cells
- Catalase
- Cell Survival
- Cells, Cultured
- Chromosomes, Human, Pair 11
- Cricetinae
- Cyclic N-Oxides
- DNA
- DNA Primers
- Gene Amplification
- Humans
- Hybrid Cells
- Hypoxanthine Phosphoribosyltransferase
- Mutagenesis
- Mutagenicity Tests