Article
Biomarkers of styrene exposure in lamination workers: levels of O6-guanine DNA adducts, DNA strand breaks and mutant frequencies in the hypoxanthine guanine phosphoribosyltransferase gene in T-lymphocytes.
Carcinogenesis - 1 Jul 1995
Vodicka P, Bastlová T, Vodicková L, Peterková K, Lambert B, Hemminki K
Abstract excerpt
Occupational exposure to styrene was studied in nine workers of a hand lamination plant in Bohemia. Personal dosimeters were used to monitor the styrene workplace exposure, and the levels of styrene in blood and mandelic acid in urine were measured. Blood samples were taken at four occasions during a 7 month period to determine styrene-specific O6-guanine DNA adducts in lymphocytes and granulocytes, DNA strand...
Topics
- Adult
- Age Factors
- Analysis of Variance
- Biomarkers
- DNA Adducts
- DNA Damage
- Environmental Monitoring
- Female
- Granulocytes
- Guanine
- Humans