Article
Aberrant function of the Ras signal transduction pathway in human breast cancer.
Breast cancer research and treatment - 1 Jul 1995
Clark G J, Der C J
Abstract excerpt
Although ras mutations are infrequent (approximately 5%) in breast cancers, there is considerable evidence that suggests that the pathways which Ras services may still be deregulated in breast cancer cells. The recent identification of many of the components of the Ras signal transduction pathway has defined a network of proto-oncogene proteins controlling diverse signaling events that regulate cell growth and...
Topics
- Apoptosis
- Breast Neoplasms
- Genes, ras
- Humans
- Mutation
- Proto-Oncogene Mas
- Proto-Oncogene Proteins p21(ras)
- Signal Transduction