Frequency and characteristics of familial aggregation of paget's disease of bone

doi:10.1002/jbmr.5650100421

Article

Frequency and characteristics of familial aggregation of paget's disease of bone

1 Apr 1995

Abstract excerpt

The cause of Paget's disease of bone (PDB) is unknown. In an attempt to ascertain the proportion of familial cases and evaluate the influence of genetic factors on the occurrence of the disease, a study was undertaken based on 35 PDB patients from our Unit. Their families were investigated, with the participation of a total of 128 first-degree relatives. Fourteen (40%) of these 35 index cases had at least one...

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