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Article

Genetics of Paget's disease of bone.

Joint bone spine - 1 May 2006

Michou Laëtitia, Collet Corinne, Laplanche Jean-Louis, Orcel Philippe, Cornélis François

Abstract excerpt

Paget's disease of bone is a chronic bone disease that affects up to 3% of Caucasians older than 55 years. The cause of Paget's disease is unknown but involves genetic factors. Familial cases display an autosomal dominant pattern of inheritance with incomplete penetrance. Genetic heterogeneity has been demonstrated and eight potential susceptibility loci identified. There is sound evidence incriminating...

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Share to Adaptor Proteins, Signal Transducing
Share to Chromosome Disorders
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16574459
DOI: 10.1016/j.jbspin.2005.05.009

Genes

SQSTM1

Provenance

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