Human helicase gene<i>SKI2W</i>in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene<i>SKI2</i>and to the human gene<i>KIAA0052:</i>emergence of a new gene family

Abstract excerpt

Helicases are essential enzymes for life because DNA replication, DNA repair, recombination, transcription, RNA splicing and translation all involve more than one helicase to unwind DNA or RNA. We have discovered, cloned and partially characterized a novel human helicase gene, SKI2W. The human SKI2W is located between the RD and RP1 genes in the class III region of the major histocompatibility complex (MHC) on...

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