Article
Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
The Journal of clinical endocrinology and metabolism - 1 Jul 1995
Takeda T, Suzuki S, Liu R T, DeGroot L J
Abstract excerpt
3,5,3,'-Triiodothyroacetic acid (Triac) has been used in therapy of resistance to thyroid hormone on an empirical basis and appears beneficial in some studies. We observed that the T3 analogs, Triac and 3,5,3'-triiodothyropropionic acid (Triprop), have a higher affinity for the thyroid hormone re...
Topics
- Base Sequence
- Cell Line
- Cloning, Molecular
- DNA Primers
- Drug Resistance
- Humans
- Kinetics
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Receptors, Thyroid Hormone
- Recombinant Proteins
- Thyroid Hormones
- Transcription, Genetic
- Transcriptional Activation
- Transfection
- Triiodothyronine