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Article

Immediate early genes and brain DNA remodeling in the Naples high- and low-excitability rat lines following exposure to a spatial novelty.

Brain research bulletin - 1 Jan 1995

Papa M, Pellicano M P, Cerbone A, Lamberti-D'Mello C, Menna T, Buono C, Giuditta A, Welzl H, Sadile A G

Abstract excerpt

The aim of these studies was to map the neural consequences of exposure to a spatial novelty on the expression of immediate gene (IEG) and on unscheduled brain DNA synthesis (UBDS) in two genetic models of altered activity and hippocampal functions, i.e., the Naples High- (NHE) and Low-excitability (NLE) rats. Adult male rats of NLE and NHE lines, and of a random-bred stock (NRB) were tested in a Làt-maze, and...

Topics

Analysis of Variance
Animals
Brain
DNA
Genes, Immediate-Early
Genotype
Italy
Male
Maze Learning
Neuronal Plasticity
Proto-Oncogene Proteins c-fos

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-jun

Rats

Rats, Mutant Strains

Rats, Sprague-Dawley

Transcription, Genetic

Source

Identifiers

PMID: 7606485
DOI: 10.1016/0361-9230(94)00254-x

Genes

FOS
JUN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7606485-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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