Article
Modulation of cell phenotype in human osteoblast-like cells by the simian virus 40.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 May 1995
Evans C E, Ng K, Allen J, Gallimore P
Abstract excerpt
At present, the majority of in vitro research into bone metabolism is performed on either primary cultures of bone or osteosarcoma lines. A better model of the behaviour of normal bone cells would be a cell line derived from normal, adult bone that retained osteoblast-like characteristics. We infected a culture of bone cells from adult humans with simian virus 1613, a variant of the simian virus 40, and obtained...
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