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Article

Multiplex genotype determination at a DNA sequence polymorphism cluster in the human immunoglobulin heavy-chain region.

Genomics - 20 Mar 1995

Li H, Hood L

Abstract excerpt

We have developed a method for multilocus genotype determination. The method involves using restriction fragment length polymorphisms (RFLPs) for allele discrimination. If a polymorphism is not an RFLP, it is converted into an RFLP during the polymerase chain reaction (PCR). After amplification and restriction enzyme digestion, samples are analyzed by sequential gel loading during electrophoresis. The efficiency...

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PMID: 7601443
DOI: 10.1016/0888-7543(95)80201-v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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