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Article

Multiplex genotype determination at a DNA sequence polymorphism cluster in the human immunoglobulin heavy-chain region.

Genomics - 20 Mar 1995

Li H, Hood L

Abstract excerpt

We have developed a method for multilocus genotype determination. The method involves using restriction fragment length polymorphisms (RFLPs) for allele discrimination. If a polymorphism is not an RFLP, it is converted into an RFLP during the polymerase chain reaction (PCR). After amplification a...

Topics

Alleles
Base Sequence
Computer Simulation
DNA
Feasibility Studies
Genes, Immunoglobulin
Genotype
Humans
Immunoglobulin Heavy Chains
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

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Identifiers

PMID: 7601443
DOI: 10.1016/0888-7543(95)80201-v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7601443-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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