Article
Characterization of mutations in the mitochondrial cytochrome b gene of Saccharomyces cerevisiae affecting the quinone reductase site (QN).
European journal of biochemistry - 15 Jun 1995
Brasseur G, Brivet-Chevillotte P
Abstract excerpt
The revertant [G33A]cytochrome b recently isolated from the [G33D]cytochrome b mutant [Coppée, J. Y., Tokutake, N., Marc, D., di Rago, J.-P., Miyoshi, H. & Colson, A.-M. (1994) FEBS Lett. 339, 1-6] exhibits cross resistance to center-N inhibitors 2-heptyl-4-hydroxyquinoline N-oxide (HQNO) and funiculosin and a spectral shift in the cytochrome b562 heme. This indicates that the conserved G33 residue is in the...
Topics
- Binding Sites
- Cytochrome b Group
- Genes, Fungal
- Mitochondria
- Mutation
- NAD(P)H Dehydrogenase (Quinone)
- Oxidation-Reduction
- Saccharomyces cerevisiae