Article
Successful xenotransplantation of human lung cancer correlates with the metastatic phenotype.
The Annals of thoracic surgery - 1 Jul 1995
Johnson J R, Hammond W G, Benfield J R, Tesluk H
Abstract excerpt
BACKGROUND: Occult micrometastases could explain deaths from stage I non-small cell lung cancer (NSCLC) after complete resections. If patients who have occult metastases could be identified, systemic therapy might be beneficial. METHODS: Non-small cell lung cancers from 81 patients in stages I, II, and III were transplanted to nude beige mice. Mean follow-up was 22.5 months (2 to 61 months). RESULTS: Twenty-one...
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