On the mechanism of skin wound "contraction": a granulation tissue "knockout" with a normal phenotype.

doi:10.1073/pnas.92.13.5982

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Article

On the mechanism of skin wound "contraction": a granulation tissue "knockout" with a normal phenotype.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jun 1995

Gross J, Farinelli W, Sadow P, Anderson R, Bruns R

Abstract excerpt

This report explores the mechanism of spontaneous closure of full-thickness skin wounds. The domestic pig, often used as a human analogue for skin wound repair studies, closes these wounds with kinetics similar to those in the guinea pig (mobile skin), even though the porcine dermis on the back i...

Topics

Animals
Disease Models, Animal
Granuloma
Humans
Kinetics
Phenotype
Skin
Swine
Time Factors
Wound Healing
Wounds and Injuries

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