Article
Cytotoxicity for lung epithelial cells is a virulence-associated phenotype of Mycobacterium tuberculosis.
Infection and immunity - 1 Dec 1995
McDonough K A, Kress Y
Abstract excerpt
Dissemination of viable tubercle bacilli from the lung is a critical event in the establishment of Mycobacterium tuberculosis infection. We examined the possibility that M. tuberculosis bacteria could infect and damage lung epithelial cells to determine whether direct penetration of the alveolar epithelium is a plausible route of M. tuberculosis infection. While both virulent H37Rv tubercle bacilli and the...
Topics
- Cell Line
- Epithelium
- Humans
- Lung
- Mycobacterium bovis
- Mycobacterium tuberculosis
- Phenotype
- Virulence