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Article

FimA, a major virulence factor associated with Streptococcus parasanguis endocarditis.

Infection and immunity - 1 Dec 1995

Burnette-Curley D, Wells V, Viscount H, Munro C L, Fenno J C, Fives-Taylor P, Macrina F L

Abstract excerpt

Adherence of microorganisms to damaged heart tissue is a crucial event in the pathogenesis of infective endocarditis. In the present study, we investigated the role of the FimA protein as a potential virulence factor associated with Streptococcus parasanguis endocarditis. FimA is a 36-kDa surface protein that is a recognized adhesin in the oral cavity where it mediates adherence to the salivary pellicle. An...

Topics

Animals
Bacterial Adhesion
Bacterial Proteins
Dental Pellicle
Endocarditis, Bacterial
Fimbriae Proteins
Humans
Male
Mutation
Platelet Adhesiveness
Platelet Aggregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Sprague-Dawley

Streptococcal Infections

Streptococcus

Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 7591121
DOI: 10.1128/iai.63.12.4669-4674.1995
PMCID: PMC173670

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7591121-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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